PRKCE
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Official Full Name
PRKCE protein kinase C, epsilon -
Synonyms
PRKCE;protein kinase C, epsilon;protein kinase C epsilon type;PKCE;nPKC-epsilon;MGC125656;MGC125657
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cells
- Sf9 Cells
- HEK293
- Insect Cells
- Sf21 Cells
- GST
- Non
- His
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
PRKCE involved in several pathways and played different roles in them. We selected most pathways PRKCE participated on our site, such as cGMP-PKG signaling pathway,Sphingolipid signaling pathway,Vascular smooth muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Vascular smooth muscle contraction | RHOA,RAF1,PRKACA,PLA2G12B,PRKCB,CALM1,ARHGEF1,MYLK4,KCNMB4,ARHGEF12 |
| Aldosterone synthesis and secretion | CYP11B2,ADCY8,CALM2,CAMK4,PRKD1,PDE2A,ATF6B,NR4A1,CALM3,PRKACB |
| MicroRNAs in cancer | STMN1,NOTCH1,CCNE1,FOXP1,CCND2,RPS6KA5,SERPINB5,HOXD10,APC,HMGA2 |
| cGMP-PKG signaling pathway | MYLK4,ITPR3,PIK3CA,PIK3R5,CREB3L3,MEF2C,VASP,CALML5,AKT1,GNAQ |
| Insulin resistance | TNFRSF1A,NFKBIAA,PTPN11B,PTPN11A,PPP1CC,PTENB,RPS6KA6,PPP1CB,PIK3R5,RELA |
| Tight junction | CRB3A,VMHCL,MYL9B,JAM3,MYL2B,EPB41L1,KRAS,EPB41L2,CASK,CLDN22 |
| Inflammatory mediator regulation of TRP channels | PPP1CB,MAPK12,BDKRB1,HTR2B,PLA2G4F,MAPK8,CYP2C39,PIK3R5,NTRK1,CYP2C37 |
| Sphingolipid signaling pathway | MAP2K1,OPRD1,SPTLC1,PRKCB,LOC100328615,PPP2R3C,FCER1A,PPP2R5D,SGMS2,GNA12 |
| Type II diabetes mellitus | PIK3R1,MAPK9,PKLR,SOCS2,IRS2,INS,INS-IGF2,HKDC1,MAPK1,PIK3CG |
Protein Function
PRKCE has several biochemical functions, for example, 14-3-3 protein binding,ATP binding,actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCE itself. We selected most functions PRKCE had, and list some proteins which have the same functions with PRKCE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 14-3-3 protein binding | RPTOR,HDAC7,ARRB2,TSC2,PRKCZ,ZFP36,KIF13B,AANAT,PPP1R12A,IRS2 |
| actin monomer binding | PFN1,TMSB,MKL1,MYL4,LMOD3,MTSS1,PKNOX2,NOS3,TMSB10,LIMA1 |
| calcium-independent protein kinase C activity | PRKCD,PRKCH |
| protein kinase C activity | PRKCHA,PRKCG,PRKCI,PKN1,PRKCDA,PRKCD,PRKCZ,PRKCH,PRKD1,PRKD3 |
| protein binding | MAP4K2,PRF1,MAB21L2,PEF1,SMCP,GRIA2,NUP50,CDK16,TACC3,TRMT1 |
| protein serine/threonine kinase activity | TRIO,PRKACAB,DCAMKL2,ACVR2B,BMPR1BA,ADCK1,MAPK12,GM4922,TSSK2,SMOK2B |
| enzyme activator activity | DCP1A,CTSA,UBA2,DCP1B,MMP16,SFTPB,MMP24,DNMT3L,ARL1,DBNL |
| receptor activator activity | PPARGC1B,IGF2 |
| enzyme binding | HDHD2,CYP2A4,HIST1H2AI,KAT8,RCOR2,PRMT1,NLRP1,HIST1H2AG,LYN,SNRPD3 |
Interacting Protein
PRKCE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCE here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCE.
YWHAZ;HSP90AB1;saicar;PKM;PECAM1;N/A;UGT1A7;IL32;BRAF;PRKCA;BAX;RPS6KA2;MAP4K4
Resources
Research Area
Intracellular Kinases in the Akt PathwayPKC Isoforms
Wnt Intracellular Signaling
Intracellular Signaling Molecules in Angiogenesis
PKC Family
Related Services
Related Products
References
